Novel Therapies and Biochemical Insights for the GM1 and GM2 Gangliosidoses
Thesis advisor: Thomas N. Seyfried === Gangliosides are glycosphingolipids (GSLs) containing sialic acids that play numerous roles in neuronal maturation, apoptotic signaling, angiogenesis, and cell surface receptor activity. The GM1 and GM2 gangliosidoses are a series of autosomal recessive lysosom...
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Format: | Others |
Language: | English |
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Boston College
2011
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Online Access: | http://hdl.handle.net/2345/3855 |