Studies of Key Enzymes Involved in the Biosynthesis of the Enediyne Antitumor Antibiotics Neocarzinostatin and C-1027

Thesis advisor: Steven D. Bruner === The enediyne antitumor antibiotics are produced by complex biosynthetic machinery in acetomycetes. This dissertation will focus on the study of three enzymes involved in key steps in the biosynthesis of two enediynes, neocarzinostatin and C-1027. Neocarzinostat...

Full description

Bibliographic Details
Main Author: Cooke, Heather A.
Format: Others
Language:English
Published: Boston College 2009
Subjects:
Online Access:http://hdl.handle.net/2345/1344