The Design, Synthesis and Characterization of Enzyme Inhibitors

Thesis advisor: Evan R. Kantrowitz === Thesis advisor: Mary F. Roberts === In this work, a series of inhibitors of two enzymes, aspartate transcarbamoylase (ATCase) and fructose 1,6-bisphosphatase (FBPase) were designed, synthesized and characterized. ATCase catalyzes the committed step in pyrimidi...

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Bibliographic Details
Main Author: Heng, Sabrina
Format: Others
Language:English
Published: Boston College 2009
Subjects:
Online Access:http://hdl.handle.net/2345/755

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