The Design, Synthesis and Characterization of Enzyme Inhibitors
Thesis advisor: Evan R. Kantrowitz === Thesis advisor: Mary F. Roberts === In this work, a series of inhibitors of two enzymes, aspartate transcarbamoylase (ATCase) and fructose 1,6-bisphosphatase (FBPase) were designed, synthesized and characterized. ATCase catalyzes the committed step in pyrimidi...
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Format: | Others |
Language: | English |
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Boston College
2009
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Online Access: | http://hdl.handle.net/2345/755 |