Characterizing the Function of PAS kinase in Cellular Metabolism and Neurodegenerative Disease

The second identified substrate of PAS kinase discussed is Pbp1. The human homolog of Pbp1 is ataxin-2, mutations in which are a known risk factor for amyotrophic lateral sclerosis (ALS). As diet and sex have been shown to be important factors regarding PAS kinase function, they also are strong cont...

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Bibliographic Details
Main Author: Pape, Jenny Adele
Format: Others
Published: BYU ScholarsArchive 2019
Subjects:
ALS
Online Access:https://scholarsarchive.byu.edu/etd/8552
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=9552&context=etd