Criteria for Selecting PEGylation Sites on Proteins for Higher Thermodynamic Stability
PEGylation of protein side-chains has been used for more than 30 years to enhance the pharmacokinetic properties of protein drugs, and has been enabled by the recent development of many chemoselective reactions for protein side-chain modification. However, there are no structure- or sequence-based g...
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| Format: | Others |
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BYU ScholarsArchive
2016
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| Online Access: | https://scholarsarchive.byu.edu/etd/6259 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7259&context=etd |