Involvement of AMPK and AP-1 Biochemical Pathways in IL-6 Regulation of Steroidogenic Enzymes in the Adrenal Cortex

Involvement of AMPK and AP-1 Biochemical Pathways in IL-6 Regulation of Steroidogenic Enzymes in the Adrenal Cortex

The adrenal cortex is a crucial endocrine gland in the mammalian stress response. In chronic inflammatory stress, cortisol is elevated whereas adrenal androgens are decreased. Furthermore, ACTH levels have poor correlation with the plasma cortisol in these conditions, thus suggesting that other fact...

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Bibliographic Details
Main Author: De Silva, Matharage Shenali
Format: Others
Published: BYU ScholarsArchive 2013
Subjects:
adrenal cortex
zona fasciculata
zona reticularis
chronic inflammatory stress
interleukin-6
AMP-activated protein kinase
activator protein-1
StAR
P450scc
SF-1
DAX-1
Cell and Developmental Biology
Physiology
Online Access:https://scholarsarchive.byu.edu/etd/4301
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5300&context=etd

Internet

https://scholarsarchive.byu.edu/etd/4301
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5300&context=etd

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