Studies Toward the Synthesis of Lyconadin A and Cranomycin
Lyconadin A is a pentacyclic Lycopodium alkaloid isolated from the club moss Lycopodium companatum with anticancer activity. Our approach sought to incorporate a 7-exo–6-exo acyl radical cyclization cascade to access the bicyclo[5.4.0]undecane framework of lyconadin A. Our studies created methodolog...
Main Author: | Loertscher, Brad M. |
---|---|
Format: | Others |
Published: |
BYU ScholarsArchive
2013
|
Subjects: | |
Online Access: | https://scholarsarchive.byu.edu/etd/4243 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5231&context=etd |
Similar Items
-
Progress Toward the Total Synthesis of Lyconadin A
by: Zhang, Yu
Published: (2009) -
An Acyl Radical Cascade Model for the Total Synthesis of Lyconadin A
by: Grant, Seth W.
Published: (2005) -
Model Studies Towards the Total Synthesis of Lyconadin A via An Acyl Radical Cascade Reaction
by: Zhu, Koudi
Published: (2006) -
Exploration of an epoxidation–ring-opening strategy for the synthesis of lyconadin A and discovery of an unexpected Payne rearrangement
by: Brad M. Loertscher, et al.
Published: (2013-06-01) -
Novel Routes to Angular and Linear Triquinanes via Radical Induced Epoxide Fragmentation-H-Abstraction-Cyclization Cascades
by: Krishnamurthy Venkat, et al.
Published: (1998-01-01)