Studies Toward the Synthesis of Lyconadin A and Cranomycin

Studies Toward the Synthesis of Lyconadin A and Cranomycin

Lyconadin A is a pentacyclic Lycopodium alkaloid isolated from the club moss Lycopodium companatum with anticancer activity. Our approach sought to incorporate a 7-exo–6-exo acyl radical cyclization cascade to access the bicyclo[5.4.0]undecane framework of lyconadin A. Our studies created methodolog...

Full description

Bibliographic Details
Main Author: Loertscher, Brad M.
Format: Others
Published: BYU ScholarsArchive 2013
Subjects:
epoxidation
pyridone synthesis
lyconadin A
tandem radical cyclization
tethered radical vinylation
Grignard addition
cranomycin
Biochemistry
Chemistry
Online Access:https://scholarsarchive.byu.edu/etd/4243
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5231&context=etd

Internet

https://scholarsarchive.byu.edu/etd/4243
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5231&context=etd

Similar Items