Susceptibility of Apoptotic Cells to Hydrolysis by sPLA2: Molecular Basis and Mechanisms Defined
Secretory phospholipase A2 hydrolyzes phospholipids at a lipid-water interface, resulting in pro-inflammatory products being released from cell membranes. Healthy cells are resistant to cleavage by this enzyme, but apoptotic cells become susceptible to its activity. Only bilayers with certain charac...
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BYU ScholarsArchive
2013
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Online Access: | https://scholarsarchive.byu.edu/etd/3690 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=4689&context=etd |