A Radical Conjugate Addition Approach to the Total Synthesis of Celogentin C

The synthesis of five chiral DBFOX (dibenzofuran-oxazoline) ligands with either aryl or benzyl substituents will be presented. The requisite amino alcohols were obtained with high enantioselectivity either commercially (DBFOX/Bn), via Sharpless asymmetric aminohydroxylation (DBFOX/Nap, DBFOX/t-BuPh,...

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Bibliographic Details
Main Author: Capps, Steven G.
Format: Others
Published: BYU ScholarsArchive 2008
Subjects:
RCA
Online Access:https://scholarsarchive.byu.edu/etd/1831
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=2830&context=etd