Mechanisms by Which Apoptotic Membranes Become Susceptible to Secretory Phospholipase A2

During apoptosis, changes occur in T-lymphocyte membranes that render them susceptible to hydrolysis by secretory phospholipase A2 (sPLA2). To study the relevant mechanisms, a simplified model of apoptosis using a calcium ionophore was first applied. Kinetic and flow cytometry experiments provided k...

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Bibliographic Details
Main Author: Bailey, Rachel Williams
Format: Others
Published: BYU ScholarsArchive 2008
Subjects:
Online Access:https://scholarsarchive.byu.edu/etd/1343
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=2342&context=etd