Structure-Activity Studies of Glycosphingolipids as Antigens of Natural Killer T Cells

Structure-Activity Studies of Glycosphingolipids as Antigens of Natural Killer T Cells

Glycosphingolipids (GSLs), composed of a polar saccharide head and a lipophilic ceramide tail, are ubiquitous components of the plasma membrane of eukaryotic cells. They serve in many regulatory capacities and have antigenic properties towards natural killer T (NKT) cells of the innate immune system...

Full description

Bibliographic Details
Main Author: Goff, Randal Donald
Format: Others
Published: BYU ScholarsArchive 2006
Subjects:
glycosphingolipid
GSL
natural killer T cell
NKT cell
alpha-galactosylceramide
ceramide
CD1d
glycolipid
Sphingomonas
Novosphingobium capsulatum
Sphingomonas paucimobilis
Ehrlichia
Ehrlichia muris
PBS-25
PBS-57
dendritic cell
DC
C-glycoside
aGalCer
KRN-7000
TH1
TH2
interferon-gamma
interleukin-4
synthesis
structure-activity relationship
Biochemistry
Chemistry
Online Access:https://scholarsarchive.byu.edu/etd/942
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=1941&context=etd

Internet

https://scholarsarchive.byu.edu/etd/942
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=1941&context=etd

Similar Items