PEGylation Stabilizes the Conformation of Proteins and the Noncovalent Interactions Within Them
PEGylation has been used for decades to enhance the pharmacokinetic properties of protein therapeutics. This method has been effective at increasing the serum half-life of these drugs, but the mechanism of how it does this is unclear. Chapter 1 is an introduction to the methods of PEGylation. In cha...
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| Format: | Others |
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BYU ScholarsArchive
2021
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| Online Access: | https://scholarsarchive.byu.edu/etd/9026 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=10035&context=etd |