The development of PI3K inhibitors as anticancer drugs

Phosphatidylinositol 3-kinases (PI3Ks) are a lipid enzyme family that are vitally important regulators of intracellular signalling pathways which control cellular activities including cell survival, growth and proliferation. Deregulation of the PI3K signalling cascade has been observed in a broad ra...

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Bibliographic Details
Main Author: Marshall, Andrew James
Other Authors: Rewcastle, Gordon
Published: ResearchSpace@Auckland 2011
Online Access:http://hdl.handle.net/2292/6440