Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

Intrinsically disordered proteins/regions (IDPs/IDRs) are proteins or peptide segments that fail to form stable 3-dimensional structures in the absence of partner proteins. They are abundant in eukaryotic proteomes and are often associated with human diseases, but their biological functions have bee...

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Main Authors: Zhang, Zhengjian (Author), Boskovic, Zarko (Author), Hu, Wenxin (Author), Inouye, Carla (Author), Kim, Han-Je (Author), Tjian, Robert (Author), Hussain, Mahmud M. (Author), Abole, A. Katherine (Author), Doud, Mary K. (Author), Lewis, Timothy A. (Author), Koehler, Angela Nicole (Contributor), Schreiber, Stuart L. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2015-11-02T20:40:14Z.
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