Strategic use of nickel(0)-catalyzed enyne-epoxide reductive coupling toward the synthesis of (−)-cyatha-3,12-diene
Various situations are explored in which the nickel(0)-catalyzed enyne-epoxide reductive coupling was utilized to access key intermediates toward the total synthesis of (−)-cyatha-3,12-diene (1). Enantioenriched 3,5-dien-1-ols with a variety of functionality were obtained in a straightforward manner...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-10-29T17:49:40Z.
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Subjects: | |
Online Access: | Get fulltext |