New synthetic strategies for the stereocontrolled synthesis of substituted 'skipped' diepoxides

This report describes a number of new synthetic approaches toward methyl-substituted mono- and diepoxy alcohols that serve as substrates for endo-selective epoxide-opening cascades. The key transformations involve the manipulation of alkynes. Highlighted are the directed methylmetalation of bishomop...

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Bibliographic Details
Main Authors: Morten, Christopher J. (Contributor), Jamison, Timothy F. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-10-29T17:45:38Z.
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