New synthetic strategies for the stereocontrolled synthesis of substituted 'skipped' diepoxides
This report describes a number of new synthetic approaches toward methyl-substituted mono- and diepoxy alcohols that serve as substrates for endo-selective epoxide-opening cascades. The key transformations involve the manipulation of alkynes. Highlighted are the directed methylmetalation of bishomop...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-10-29T17:45:38Z.
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Subjects: | |
Online Access: | Get fulltext |