Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1
Translesion DNA synthesis (TLS) functions as a tolerance mechanism for DNA damage at a potentially mutagenic cost. Three TLS polymerases (Pols) function to bypass DNA damage in Saccharomyces cerevisiae: Rev1, Pol ζ, a heterodimer of the Rev3 and Rev7 proteins, and Pol η (Rad30). Our lab has shown th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier,
2015-10-07T15:10:05Z.
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| Subjects: | |
| Online Access: | Get fulltext |