Stepwise Unfolding of a β Barrel Protein by the AAA+ ClpXP Protease
In the AAA+ ClpXP protease, ClpX uses the energy of ATP binding and hydrolysis to unfold proteins before translocating them into ClpP for degradation. For proteins with C-terminal ssrA tags, ClpXP pulls on the tag to initiate unfolding and subsequent degradation. Here, we demonstrate that an initial...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier,
2015-10-06T19:23:34Z.
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| Subjects: | |
| Online Access: | Get fulltext |