α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo

α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo

The RGD-binding α5 and αv integrins have been shown to be key regulators of vascular smooth muscle cell (vSMC) function in vitro. However, their role on vSMCs during vascular development in vivo remains unclear. To address this issue, we have generated mice that lack α5, αv or both α5 and αv integri...

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Bibliographic Details
Main Authors: Turner, Christopher J. (Contributor), Badu-Nkansah, Kwabena (Contributor), Crowley, Denise G. (Contributor), van der Flier, Arjan (Contributor), Hynes, Richard O (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Hynes, Richard O. (Contributor)
Format: Article
Language:English
Published: Company of Biologists, 2015-08-20T18:39:02Z.
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