Tumor Angiogenesis in the Absence of Fibronectin or Its Cognate Integrin Receptors
Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in the extracellular matrix has been targeted as a possible means of blocking tumor angiogenesis and tumor growth. However, clinical trials of blocking antibodies and peptides have been disappointing des...
| Main Authors: | , , |
|---|---|
| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science,
2015-05-29T14:37:34Z.
|
| Subjects: | |
| Online Access: | Get fulltext |