Synthetic Methods for the Preparation of Platinum Anticancer Complexes

The demonstration in the 1960s that cis-diammine-dichloroplatinum(II), or cisplatin, inhibits cellular division of Escherichia coli led to the subsequent discovery that this simple coordination compound is also an effective antitumor agent in mouse models. Subsequent studies validated cisplatin as a...

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Bibliographic Details
Main Authors: Wilson, Justin J. (Contributor), Lippard, Stephen J. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-04-30T15:43:42Z.
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