Genome-wide localization of small molecules

Genome-wide localization of small molecules

A vast number of small-molecule ligands, including therapeutic drugs under development and in clinical use, elicit their effects by binding specific proteins associated with the genome. An ability to map the direct interactions of a chemical entity with chromatin genome-wide could provide important...

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Bibliographic Details
Main Authors: Anders, Lars (Author), Guenther, Matthew G. (Author), Qi, Jun (Author), Fan, Zi Peng (Contributor), Marineau, Jason J (Author), Rahl, Peter B (Author), Sigova, Alla A (Author), Smith, William B (Author), Lee, Tong Ihn (Author), Bradner, James E. (Author), Young, Richard A. (Contributor), Loven, Jakob (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-04-30T12:42:34Z.
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