Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition
Characterizing changes in protein-protein interactions associated with sequence variants (e.g., disease-associated mutations or splice forms) or following exposure to drugs, growth factors or hormones is critical to understanding how protein complexes are built, localized and regulated. Affinity pur...
Main Authors: | Lambert, Jean-Philippe (Author), Ivosev, Gordana (Author), Couzens, Amber L (Author), Larsen, Brett (Author), Taipale, Mikko (Author), Lin, Zhen-Yuan (Author), Zhong, Quan (Author), Lindquist, Susan (Contributor), Vidal, Marc (Author), Aebersold, Ruedi (Author), Pawson, Tony (Author), Bonner, Ron (Author), Tate, Stephen (Author), Gingras, Anne-Claude (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2015-04-21T18:50:58Z.
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Subjects: | |
Online Access: | Get fulltext |
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