Transcriptional profiling of cells sorted by transcript abundance

Transcriptional profiling of cells sorted by transcript abundance

We have developed a quantitative technique for sorting cells on the basis of endogenous RNA abundance, with a molecular resolution of 10-20 transcripts. We demonstrate efficient and unbiased RNA extraction from transcriptionally sorted cells and report a high-fidelity transcriptome measurement of mo...

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Bibliographic Details
Main Authors: Klemm, Sandy Lee (Contributor), Semrau, Stefan (Contributor), Wiebrands, Kay (Author), Mooijman, Dylan (Author), Jaenisch, Rudolf (Contributor), van Oudenaarden, Alexander (Contributor), Faddah, Dina A. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-04-10T17:20:03Z.
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