Poly(A)-tail profiling reveals an embryonic switch in translational control

Poly(A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here we describe poly(A)-tail length profiling by sequencing (PAL-seq) and apply it to measu...

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Bibliographic Details
Main Authors: Subtelny, Alexander Orest (Contributor), Eichhorn, Stephen William (Contributor), Chen, Grace (Contributor), Sive, Hazel L. (Contributor), Bartel, David (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-03-27T18:08:51Z.
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