Oxidative halogenation of cisplatin and carboplatin: synthesis, spectroscopy, and crystal and molecular structures of Pt(IV) prodrugs
A series of Pt(IV) prodrugs has been obtained by oxidative halogenation of either cisplatin or carboplatin. Iodobenzene dichloride is a general reagent that cleanly provides prodrugs bearing axial chlorides without the need to prepare intervening Pt(IV) intermediates or handle chlorine gas. Elementa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry, The,
2015-02-24T15:26:13Z.
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| Subjects: | |
| Online Access: | Get fulltext |