Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

Dogs, with their breed-determined limited genetic background, are great models of human disease including cancer. Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically similar to human B-cell non-Hodgkin lymphoma and angiosa...

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Main Authors: Tonomura, Noriko (Author), Elvers, Ingegerd (Author), Thomas, Rachael (Author), Megquier, Kate (Author), Turner-Maier, Jason (Author), Howald, Cedric (Author), Sarver, Aaron L. (Author), Swofford, Ross (Author), Frantz, Aric M. (Author), Ito, Daisuke (Author), Mauceli, Evan (Author), Arendt, Maja (Author), Noh, Hyun Ji (Author), Koltookian, Michele (Author), Biagi, Tara (Author), Fryc, Sarah (Author), Williams, Christina (Author), Avery, Anne C. (Author), Kim, Jong-Hyuk (Author), Barber, Lisa (Author), Burgess, Kristine (Author), Karlsson, Elinor K (Author), Azuma, Chieko (Author), Modiano, Jaime F. (Author), Breen, Matthew (Author), Lindblad-Toh, Kerstin (Author), Lander, Eric Steven (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Lander, Eric S. (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2015-02-18T18:27:02Z.
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