Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

We developed modified RBCs to serve as carriers for systemic delivery of a wide array of payloads. These RBCs contain modified proteins on their plasma membrane, which can be labeled in a sortase-catalyzed reaction under native conditions without inflicting damage to the target membrane or cell. Sor...

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Bibliographic Details
Main Authors: Shi, Jiahai (Contributor), Kundrat, Lenka (Contributor), Pishesha, Novalia (Contributor), Bilate, Angelina M. (Contributor), Theile, Christopher S. (Contributor), Maruyama, Takeshi (Contributor), Dougan, Stephanie K. (Contributor), Ploegh, Hidde (Contributor), Lodish, Harvey F. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-02-04T15:45:13Z.
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