End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

A series of tubes: The continuous manufacture of a finished drug product starting from chemical intermediates is reported. The continuous pilot-scale plant used a novel route that incorporated many advantages of continuous-flow processes to produce active pharmaceutical ingredients and the drug prod...

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Bibliographic Details
Main Authors: Mascia, Salvatore (Contributor), Heider, Patrick L. (Contributor), Zhang, Haitao (Contributor), Lakerveld, Richard (Contributor), Benyahia, Brahim (Contributor), Barton, Paul I. (Contributor), Braatz, Richard D. (Contributor), Cooney, Charles L. (Contributor), Evans, James M. B. (Contributor), Jamison, Timothy F. (Contributor), Jensen, Klavs F. (Contributor), Myerson, Allan S. (Contributor), Trout, Bernhardt L. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2014-12-23T14:17:13Z.
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