The Membrane Environment Can Promote or Suppress Bistability in Cell Signaling Networks

The Membrane Environment Can Promote or Suppress Bistability in Cell Signaling Networks

Many key biochemical reactions that mediate signal transduction in cells occur at the cell membrane, yet how the two-dimensional membrane environment influences the collective behavior of signaling networks is poorly understood. We study models of two topologically different signaling pathways that...

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Bibliographic Details
Main Authors: Abel, Steven M. (Contributor), Roose, Jeroen P. (Author), Groves, Jay T. (Author), Weiss, Arthur (Author), Chakraborty, Arup K (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Chakraborty, Arup K. (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2014-10-29T13:47:27Z.
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