Age- and diabetes-related nonenzymatic crosslinks in collagen fibrils: Candidate amino acids involved in Advanced Glycation End-products

Ageing and diabetes share a common deleterious phenomenon, the formation of Advanced Glycation Endproducts (AGEs), which accumulate predominantly in collagen due to its low turnover. Though the general picture of glycation has been identified, the detailed knowledge of which collagen amino acids are...

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Bibliographic Details
Main Authors: Gautieri, Alfonso (Contributor), Redaelli, Alberto (Author), Vesentini, Simone (Author), Buehler, Markus J (Author)
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor), Massachusetts Institute of Technology. Laboratory for Atomistic and Molecular Mechanics (Contributor), Massachusetts Institute of Technology. School of Engineering (Contributor), Buehler, Markus J. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-09-09T12:38:56Z.
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