Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G In Vivo

The apolipoprotein B editing complex 3 (A3) cytidine deaminases are among the most highly evolutionarily selected retroviral restriction factors, both in terms of gene copy number and sequence diversity. Primate genomes encode seven A3 genes, and while A3F and 3G are widely recognized as important i...

Full description

Bibliographic Details
Main Authors: Stavrou, Spyridon (Author), Crawford, Daniel (Author), Blouch, Kristin (Author), Browne, Edward P. (Contributor), Kohli, Rahul M. (Author), Ross, Susan R. (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2014-07-01T16:51:56Z.
Subjects:
Online Access:Get fulltext