PSD95 Suppresses Dendritic Arbor Development in Mature Hippocampal Neurons by Occluding the Clustering of NR2B-NMDA Receptors

PSD95 Suppresses Dendritic Arbor Development in Mature Hippocampal Neurons by Occluding the Clustering of NR2B-NMDA Receptors

Considerable evidence indicates that the NMDA receptor (NMDAR) subunits NR2A and NR2B are critical mediators of synaptic plasticity and dendritogenesis; however, how they differentially regulate these processes is unclear. Here we investigate the roles of the NR2A and NR2B subunits, and of their sca...

Full description

Bibliographic Details
Main Authors: Bustos, Fernando J. (Author), Varela-Nallar, Lorena (Author), Campos, Matias (Author), Henriquez, Berta (Author), Phillips, Marnie (Contributor), Opazo, Carlos (Author), Aguayo, Luis G. (Author), Montecino, Martin (Author), Constantine-Paton, Martha (Contributor), Inestrosa, Nibaldo C. (Author), van Zundert, Brigitte (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2014-06-30T13:03:08Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items