Evaluating the impact of genotype errors on rare variant tests of association

The new class of rare variant tests has usually been evaluated assuming perfect genotype information. In reality, rare variant genotypes may be incorrect, and so rare variant tests should be robust to imperfect data. Errors and uncertainty in SNP genotyping are already known to dramatically impact s...

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Bibliographic Details
Main Authors: Cook, Kaitlyn (Author), Benitez, Alejandra (Author), Fu, Casey L. (Contributor), Tintle, Nathan (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mathematics (Contributor)
Format: Article
Language:English
Published: Frontiers Research Foundation, 2014-06-20T15:45:00Z.
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