Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach

Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach

Background: Accurate estimation of parameters of biochemical models is required to characterize the dynamics of molecular processes. This problem is intimately linked to identifying the most informative experiments for accomplishing such tasks. While significant progress has been made, effective exp...

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Main Authors: Meyer, Pablo (Author), Cokelaer, Thomas (Author), Chandran, Deepak (Author), Kim, Kyung H. (Author), Loh, Po-Ru (Contributor), Lipson, Mark (Contributor), Berger, Bonnie (Contributor), Kreutz, Clemens (Author), Raue, Andreas (Author), Steiert, Bernhard (Author), Timmer, Jens (Author), Bilal, Erhan (Author), DREAM 6&7 Parameter Estimation consortium (Author), Sauro, Herbert M. (Author), Stolovitzky, Gustavo (Author), Saez-Rodriguez, Julio (Author), Tucker, George Jay (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Mathematics (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd, 2014-04-03T19:05:12Z.
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