Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution

Thousands of long intervening noncoding RNAs (lincRNAs) have been identified in mammals. To better understand the evolution and functions of these enigmatic RNAs, we used chromatin marks, poly(A)-site mapping and RNA-Seq data to identify more than 550 distinct lincRNAs in zebrafish. Although these s...

Full description

Bibliographic Details
Main Authors: Ulitsky, Igor (Contributor), Shkumatava, Alena (Contributor), Jan, Calvin H. (Contributor), Sive, Hazel L. (Contributor), Bartel, David (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2014-02-07T17:54:02Z.
Subjects:
Online Access:Get fulltext