Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year. Overtreatment of indolent disease also results in significant morbidity. Common genetic alterations in prostate cancer include losses of NKX3.1 (8p21) and PTEN (10q23), gains of AR (the androg...

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Main Authors: Barbieri, Christopher E. (Author), Baca, Sylvan C. (Author), Lawrence, Michael S. (Author), Demichelis, Francesca (Author), Blattner, Mirjam (Author), Theurillat, Jean-Philippe (Author), White, Thomas A. (Author), Stojanov, Petar (Author), Van Allen, Eliezer (Author), Stransky, Nicolas (Author), Nickerson, Elizabeth (Author), Chae, Sung-Suk (Author), Boysen, Gunther (Author), Auclair, Daniel (Author), Onofrio, Robert (Author), Park, Kyung (Author), Kitabayashi, Naoki (Author), MacDonald, Theresa Y. (Author), Sheikh, Karen (Author), Lander, Eric Steven (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Lander, Eric S. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-02-03T20:16:49Z.
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