Progressive Genomic Instability in the FVB/Kras[superscript LA2] Mouse Model of Lung Cancer

Progressive Genomic Instability in the FVB/Kras[superscript LA2] Mouse Model of Lung Cancer

Alterations in DNA copy number contribute to the development and progression of cancers and are common in epithelial tumors. We have used array Comparative Genomic Hybridization (aCGH) to visualize DNA copy number alterations across the genomes of lung tumors in the Kras[superscript LA2] model of lu...

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Bibliographic Details
Main Authors: To, Minh D. (Author), Quigley, David A. (Author), Mao, Jian-Hua (Author), Del Rosario, Reyno (Author), Hsu, Jeff (Author), Hodgson, Graeme (Author), Balmain, Allan (Author), Jacks, Tyler E (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Jacks, Tyler E. (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research, 2014-02-03T16:42:08Z.
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