A complex network of factors with overlapping affinities represses splicing through intronic elements
To better understand splicing regulation, we used a cell-based screen to identify ten diverse motifs that inhibit splicing from introns. Motifs were validated in another human cell type and gene context, and their presence correlated with in vivo splicing changes. All motifs exhibited exonic splicin...
Main Authors: | , , , , , , , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2014-01-27T18:13:51Z.
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Subjects: | |
Online Access: | Get fulltext |