Interaction between Poly(ADP-ribose) and NuMA Contributes to Mitotic Spindle Pole Assembly
Poly(ADP-ribose) (pADPr), made by PARP-5a/tankyrase-1, localizes to the poles of mitotic spindles and is required for bipolar spindle assembly, but its molecular function in the spindle is poorly understood. To investigate this, we localized pADPr at spindle poles by immuno-EM. We then developed a c...
| Main Authors: | , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
American Society for Cell Biology,
2014-01-27T16:35:12Z.
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| Subjects: | |
| Online Access: | Get fulltext |