CYSL-1 Interacts with the O[subscript 2]-Sensing Hydroxylase EGL-9 to Promote H[subscript 2]S-Modulated Hypoxia-Induced Behavioral Plasticity in C. elegans
The C. elegans HIF-1 proline hydroxylase EGL-9 functions as an O[subscript 2] sensor in an evolutionarily conserved pathway for adaptation to hypoxia. H[subscript 2]S accumulates during hypoxia and promotes HIF-1 activity, but how H[subscript 2]S signals are perceived and transmitted to modulate HIF...
Main Authors: | , , , |
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Other Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2014-01-24T19:21:23Z.
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Subjects: | |
Online Access: | Get fulltext |