Hypoxia promotes liver stage malaria infection in primary human hepatocytes in vitro

Hypoxia promotes liver stage malaria infection in primary human hepatocytes in vitro

Homeostasis of mammalian cell function strictly depends on balancing oxygen exposure to maintain energy metabolism without producing excessive reactive oxygen species. In vivo, cells in different tissues are exposed to a wide range of oxygen concentrations, and yet in vitro models almost exclusively...

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Main Authors: Ng, Shengyong (Contributor), March-Riera, Sandra (Contributor), Galstian, Ani (Contributor), Hanson, Kirsten (Author), Carvalho, Tania (Author), Mota, Maria M. (Author), Bhatia, Sangeeta N (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Bhatia, Sangeeta N. (Contributor)
Format: Article
Language:English
Published: Company of Biologists, 2013-12-13T18:41:23Z.
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