Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery

Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery

The identification of cancer drivers is a major goal of current cancer research. Finding driver genes within large chromosomal events is especially challenging because such alterations encompass many genes. Previously, we demonstrated that zebrafish malignant peripheral nerve sheath tumors (MPNSTs)...

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Bibliographic Details
Main Authors: Zhang, GuangJun (Contributor), Hoersch, Sebastian (Contributor), Amsterdam, Adam (Contributor), Whittaker, Charles A. (Contributor), Beert, Eline (Author), Catchen, Julian M. (Author), Postlethwait, John H. (Author), Legius, Eric (Author), Farrington, Sarah M. (Contributor), Hopkins, Nancy H. (Contributor), Lees, Jacqueline (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-09-30T17:15:17Z.
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