Time-dependent bending rigidity and helical twist of DNA by rearrangement of bound HU protein

HU is a protein that plays a role in various bacterial processes including compaction, transcription and replication of the genome. Here, we use atomic force microscopy to study the effect of HU on the stiffness and supercoiling of double-stranded DNA. First, we measured the persistence length, heig...

Full description

Bibliographic Details
Main Authors: Doyle, Patrick S. (Contributor), Kundukad, Binu (Author), Cong, Piewen (Author), van der Maarel, Johan R. C. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2013-09-13T16:13:09Z.
Subjects:
Online Access:Get fulltext