Morphine Epigenomically Regulates Behavior through Alterations in Histone H3 Lysine 9 Dimethylation in the Nucleus Accumbens

Morphine Epigenomically Regulates Behavior through Alterations in Histone H3 Lysine 9 Dimethylation in the Nucleus Accumbens

Dysregulation of histone modifying enzymes has been associated with numerous psychiatric disorders. Alterations in G9a (Ehmt2), a histone methyltransferase that catalyzes the euchromatic dimethylation of histone H3 at lysine 9 (H3K9me2), has been implicated recently in mediating neural and behaviora...

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Main Authors: Sun, Hao Sheng (Author), Maze, Ian (Author), Dietz, David M. (Author), Scobie, Kimberly N. (Author), Kennedy, Pamela J. (Author), Damez-Werno, Diane (Author), Neve, Rachael L. (Contributor), Zachario, Venetia (Author), Shen, Li (Author), Nestler, Eric J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: Society for Neuroscience, 2013-06-20T15:45:21Z.
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