Confinement to Organelle-Associated Inclusion Structures Mediates Asymmetric Inheritance of Aggregated Protein in Budding Yeast

The division of the S. cerevisiae budding yeast, which produces one mother cell and one daughter cell, is asymmetric with respect to aging. Remarkably, the asymmetry of yeast aging coincides with asymmetric inheritance of damaged and aggregated proteins by the mother cell. Here, we show that misfold...

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Bibliographic Details
Main Authors: Spokoini, Rachel (Author), Moldavski, Ofer (Author), Nahmias, Yaakov (Author), England, Jeremy L. (Contributor), Schuldiner, Maya (Author), Kaganovich, Daniel (Author)
Other Authors: Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Elsevier, 2013-03-13T19:25:11Z.
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