Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome

Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome

Changes in the physical interaction between cis-regulatory DNA sequences and proteins drive the evolution of gene expression. However, it has proven difficult to accurately quantify evolutionary rates of such binding change or to estimate the relative effects of selection and drift in shaping the bi...

Full description

Bibliographic Details
Main Authors: Chen, Sidi (Contributor), Ni, Xiaochun (Author), Long, Manyuan (Author), Negre, Nicolas (Author), Zhang, Yong E. (Author), White, Kevin P. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-02-21T19:28:54Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items