Distinguishing direct versus indirect transcription factor-DNA interactions

Transcriptional regulation is largely enacted by transcription factors (TFs) binding DNA. Large numbers of TF binding motifs have been revealed by ChIP-chip experiments followed by computational DNA motif discovery. However, the success of motif discovery algorithms has been limited when applied to...

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Bibliographic Details
Main Authors: Gordan, Raluca (Author), Hartemink, Alexander J. (Author), Bulyk, Martha L. (Contributor)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2013-02-06T20:56:46Z.
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